{"id":11402152,"date":"2026-07-13T08:09:30","date_gmt":"2026-07-13T05:09:30","guid":{"rendered":"https:\/\/nostylelike.net\/product\/cyclo-progynova-21-tablets\/"},"modified":"2026-07-14T03:22:01","modified_gmt":"2026-07-14T00:22:01","slug":"cyclo-progynova-21-tablets","status":"publish","type":"product","link":"https:\/\/nostylelike.net\/en\/product\/cyclo-progynova-21-tablets\/","title":{"rendered":"Cyclo-Progynova 21 Tablets \u2013 Hormone Regulation for Women"},"content":{"rendered":"<div style=\"background: #fff3f3; border: 2px solid #d9534f; padding: 14px 18px; border-radius: 8px; margin-bottom: 20px;\"><strong>&#x26a0;&#xfe0f; Prescription-Only Medicine:<\/strong> Cyclo-Progynova is a hormonal medication that must only be used under the supervision of a physician. Do not start, stop, or change the dose without consulting your doctor.<\/div>\n<nav style=\"background: #faf7fc; border: 1px solid #eee; padding: 14px 18px; border-radius: 8px; margin-bottom: 20px;\"><strong>Table of Contents<\/strong><\/p>\n<ul style=\"margin: 8px 0 0; padding-left: 18px;\">\n<li><a href=\"#what-is\">What Is Cyclo-Progynova?<\/a><\/li>\n<li><a href=\"#key-facts\">Key Facts<\/a><\/li>\n<li><a href=\"#how-works\">How It Works<\/a><\/li>\n<li><a href=\"#uses\">Medical Uses<\/a><\/li>\n<li><a href=\"#dosage\">How to Take the 21-Day Course<\/a><\/li>\n<li><a href=\"#contra\">Contraindications<\/a><\/li>\n<li><a href=\"#side-effects\">Side Effects<\/a><\/li>\n<li><a href=\"#interactions\">Drug Interactions<\/a><\/li>\n<li><a href=\"#faq\">FAQ<\/a><\/li>\n<\/ul>\n<\/nav>\n<div style=\"background: #fff4f7; border-left: 4px solid #b32d5e; padding: 14px 18px; border-radius: 6px; margin-bottom: 20px;\"><strong>Quick Answer:<\/strong> Cyclo-Progynova by Bayer is a prescription hormone therapy of 21 tablets \u2014 11 white tablets containing estradiol valerate 2 mg, followed by 10 brown tablets combining estradiol valerate 2 mg with norgestrel 0.5 mg. Doctors prescribe it to correct estrogen deficiency, regulate irregular or absent menstrual cycles, and manage menopausal symptoms.<\/div>\n<h2 id=\"what-is\">What Is Cyclo-Progynova?<\/h2>\n<p><strong>Cyclo-Progynova<\/strong> is a cyclical hormone replacement therapy (HRT) manufactured by Bayer. Each pack covers a 21-day course that mimics the natural rhythm of a woman&#8217;s cycle: the first 11 white tablets deliver estrogen alone (estradiol valerate 2 mg), and the following 10 brown tablets add a progestogen (norgestrel 0.5 mg) to protect the uterine lining.<\/p>\n<p>Because hormones control ovulation, menstruation, bone density, and many other functions, physicians use Cyclo-Progynova when a woman&#8217;s own estrogen production is insufficient \u2014 a situation that can cause irregular periods, absent periods (secondary amenorrhea), or menopausal complaints. <em>It is available only with a valid prescription.<\/em><\/p>\n<p><img decoding=\"async\" style=\"max-width: 100%; height: auto;\" src=\"https:\/\/nostylelike.net\/wp-content\/uploads\/2022\/08\/454238.jpg\" alt=\"Cyclo-Progynova 21 tablets pack by Bayer for hormone regulation\" \/><\/p>\n<h2 id=\"key-facts\">Key Facts<\/h2>\n<table style=\"width: 100%; border-collapse: collapse;\">\n<tbody>\n<tr>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\"><strong>Active ingredients<\/strong><\/td>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\">Estradiol valerate 2 mg (11 white tablets); estradiol valerate 2 mg + norgestrel 0.5 mg (10 brown tablets)<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\"><strong>Manufacturer<\/strong><\/td>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\">Bayer<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\"><strong>Pack size<\/strong><\/td>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\">21 tablets (one cycle)<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\"><strong>Barcode (GTIN)<\/strong><\/td>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\">8699546120048<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\"><strong>Classification<\/strong><\/td>\n<td style=\"border: 1px solid #e5e5e5; padding: 8px;\">Prescription-only hormonal medicine (HRT)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"how-works\">How Cyclo-Progynova Works<\/h2>\n<p>The estrogen phase restores circulating estradiol, relieving symptoms of deficiency such as hot flushes, mood changes, and vaginal dryness, while supporting the build-up of the uterine lining. The combined estrogen-progestogen phase then stabilizes and organizes that lining so it can shed in a controlled, regular withdrawal bleed \u2014 which is why doctors also use Cyclo-Progynova to regulate absent or chaotic cycles. <strong>Note:<\/strong> Cyclo-Progynova is not a contraceptive and does not reliably prevent pregnancy.<\/p>\n<h2 id=\"uses\">Medical Uses (Doctor-Prescribed Only)<\/h2>\n<ul>\n<li>Hormone replacement therapy for estrogen deficiency after menopause or ovarian insufficiency.<\/li>\n<li>Regulation of irregular menstrual cycles caused by hormonal imbalance.<\/li>\n<li>Secondary amenorrhea (absent periods) after pregnancy has been excluded.<\/li>\n<li>Support within fertility plans in selected cases, strictly at the treating physician&#8217;s discretion.<\/li>\n<\/ul>\n<h2 id=\"dosage\">How to Take the 21-Day Course<\/h2>\n<p>The usual pattern prescribed by physicians: one white tablet daily for 11 days, then one brown tablet daily for 10 days, followed by a 7-day tablet-free break during which a withdrawal bleed usually occurs. The next pack starts after the break. Take the tablet at the same time every day, swallowed whole with water. <strong>&#x26a0;&#xfe0f; Always follow your own doctor&#8217;s instructions \u2014 regimens are individualized.<\/strong><\/p>\n<h2 id=\"contra\">Contraindications \u2014 Do NOT Use If<\/h2>\n<div style=\"background: #fff3f3; border-left: 4px solid #d9534f; padding: 14px 18px; border-radius: 6px; margin-bottom: 16px;\">\n<p style=\"margin: 0;\">Cyclo-Progynova must not be used in women with any of the following. Your doctor will review your full history before prescribing:<\/p>\n<\/div>\n<ul>\n<li>Known, suspected, or previous <strong>breast cancer<\/strong> or other estrogen-dependent tumors.<\/li>\n<li>History of <strong>venous thromboembolism<\/strong> (deep vein thrombosis, pulmonary embolism) or known clotting disorders.<\/li>\n<li>Recent heart attack, stroke, or angina.<\/li>\n<li>Active or previous <strong>liver disease<\/strong> with abnormal liver function.<\/li>\n<li>Undiagnosed vaginal bleeding.<\/li>\n<li><strong>Pregnancy or breastfeeding<\/strong> \u2014 stop immediately and contact your doctor if pregnancy occurs.<\/li>\n<li>Porphyria or known allergy to any component.<\/li>\n<\/ul>\n<h2 id=\"side-effects\">Possible Side Effects<\/h2>\n<p>Like all hormonal medicines, Cyclo-Progynova can cause side effects. Common ones include headache, breast tenderness, nausea, bloating, breakthrough spotting in the first months, and mood or weight changes. <strong>Seek urgent medical care<\/strong> for warning signs of a blood clot: painful swelling in one leg, sudden chest pain, breathlessness, or sudden severe headache or vision change. Long-term HRT is associated with a small increased risk of breast cancer and thromboembolism \u2014 your doctor weighs benefits against risks yearly.<\/p>\n<h2 id=\"interactions\">Drug Interactions<\/h2>\n<p>Tell your doctor about every medicine and supplement you take. Enzyme-inducing drugs can reduce Cyclo-Progynova&#8217;s effect: certain <strong>epilepsy medicines<\/strong> (carbamazepine, phenytoin, phenobarbital), <strong>rifampicin<\/strong> (tuberculosis), some <strong>HIV\/HCV antivirals<\/strong>, and the herbal supplement <strong>St. John&#8217;s Wort<\/strong>. Hormone therapy may also alter the needs of <strong>diabetes and thyroid medications<\/strong>.<\/p>\n<div style=\"background: #f4faf6; border-left: 4px solid #2e8b57; padding: 14px 18px; border-radius: 6px; margin: 20px 0;\"><strong>Expert Note \u2014 Dr. Abdallah Fouad, Clinical Nutrition Specialist (25+ years of experience):<\/strong> &#8220;With any hormonal therapy, lifestyle strongly influences results. I advise patients on Cyclo-Progynova to stop smoking \u2014 it multiplies clotting risk \u2014 keep vitamin D and calcium adequate for bone health, and never borrow or share hormone tablets. This medicine is safe only when it is <em>your<\/em> prescription.&#8221;<\/div>\n<p>Browse related sections: <a href=\"https:\/\/nostylelike.net\/en\/product-category\/hormonal-medications\/\">Hormonal Medications<\/a>, <a href=\"https:\/\/nostylelike.net\/en\/product-category\/fertility-pregnancy\/\">Fertility &amp; Pregnancy<\/a>, our <a href=\"https:\/\/nostylelike.net\/en\/best-sellers\/\">Best Sellers<\/a>, the <a href=\"https:\/\/nostylelike.net\/en\/shop\/\">full shop<\/a>, or <a href=\"https:\/\/nostylelike.net\/en\/contact-us\/\">contact us<\/a> with your prescription for availability.<\/p>\n<h2 id=\"faq\">Frequently Asked Questions<\/h2>\n<details>\n<summary><strong>Is Cyclo-Progynova a contraceptive?<\/strong><\/summary>\n<p>No. It does not reliably prevent pregnancy. Women who need contraception must use a separate non-hormonal method as advised by their doctor.<\/p>\n<\/details>\n<details>\n<summary><strong>When does the period come while using it?<\/strong><\/summary>\n<p>A withdrawal bleed usually occurs during the 7-day break after finishing the 21 tablets.<\/p>\n<\/details>\n<details>\n<summary><strong>What if I miss a tablet?<\/strong><\/summary>\n<p>Take it as soon as remembered if less than 24 hours late; otherwise skip it and continue. Missed tablets increase the chance of spotting. Ask your doctor for specific guidance.<\/p>\n<\/details>\n<details>\n<summary><strong>Can it help me get pregnant?<\/strong><\/summary>\n<p>Only a treating fertility specialist can decide if it fits your plan. It is not a fertility drug by itself and is never used during pregnancy.<\/p>\n<\/details>\n<details>\n<summary><strong>Can I buy Cyclo-Progynova without a prescription?<\/strong><\/summary>\n<p>No. It is a prescription-only medicine. A valid prescription is required, and your doctor must supervise the treatment.<\/p>\n<\/details>\n<details>\n<summary><strong>Does it cause weight gain?<\/strong><\/summary>\n<p>Some women report fluid retention or appetite changes; significant weight change should be discussed with your doctor.<\/p>\n<\/details>\n<details>\n<summary><strong>Is it safe for smokers?<\/strong><\/summary>\n<p>Smoking substantially raises the risk of blood clots with estrogen therapy. Doctors strongly advise quitting before starting HRT.<\/p>\n<\/details>\n<h2 id=\"disclaimer\">Medical Disclaimer<\/h2>\n<p><em>This page is for education only and does not replace professional medical advice. Cyclo-Progynova is a prescription-only medicine: use it exclusively under the supervision of your physician, who determines whether it suits your medical history. Never self-prescribe hormonal therapy.<\/em><\/p>\n<p><strong>References:<\/strong> <a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/6551\/smpc\" target=\"_blank\" rel=\"noopener nofollow\">EMC \u2013 Cyclo-Progynova SmPC<\/a> \u00b7 <a href=\"https:\/\/www.nhs.uk\/medicines\/hormone-replacement-therapy-hrt\/\" target=\"_blank\" rel=\"noopener nofollow\">NHS \u2013 Hormone Replacement Therapy<\/a> \u00b7 <a href=\"https:\/\/www.bayer.com\" target=\"_blank\" rel=\"noopener nofollow\">Bayer<\/a><\/p>\n<p style=\"font-size: 0.9em; color: #666;\">Reviewed by <strong>Dr. Abdallah Fouad, Clinical Nutrition Specialist \u2014 25+ years of experience<\/strong> \u00b7 nostylelike.net<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>&#x26a0;&#xfe0f; Prescription-only medicine.<\/strong> <strong>Cyclo-Progynova<\/strong> by Bayer \u2014 21-tablet cyclical hormone therapy (estradiol valerate + norgestrel) prescribed to correct estrogen deficiency and regulate menstrual cycles.<\/p>\n<table style=\"width: 100%; border-collapse: collapse;\">\n<tbody>\n<tr>\n<td style=\"border: 1px solid #eee; padding: 6px;\"><strong>Active ingredients<\/strong><\/td>\n<td style=\"border: 1px solid #eee; padding: 6px;\">Estradiol valerate 2 mg \/ + Norgestrel 0.5 mg<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #eee; padding: 6px;\"><strong>Pack<\/strong><\/td>\n<td style=\"border: 1px solid #eee; padding: 6px;\">21 tablets (11 white + 10 brown)<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #eee; padding: 6px;\"><strong>Manufacturer<\/strong><\/td>\n<td style=\"border: 1px solid #eee; padding: 6px;\">Bayer<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #eee; padding: 6px;\"><strong>Status<\/strong><\/td>\n<td style=\"border: 1px solid #eee; padding: 6px;\">Prescription Only (Rx)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":11214384,"template":"","meta":[],"product_brand":[],"product_cat":[42013,41623],"product_tag":[],"class_list":["post-11402152","product","type-product","status-publish","has-post-thumbnail","product_cat-fertility-pregnancy","product_cat-hormonal-medications","first","outofstock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product\/11402152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":2,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product\/11402152\/revisions"}],"predecessor-version":[{"id":11402715,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product\/11402152\/revisions\/11402715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/media\/11214384"}],"wp:attachment":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/media?parent=11402152"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product_brand?post=11402152"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product_cat?post=11402152"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product_tag?post=11402152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}