{"id":11402203,"date":"2026-07-13T14:43:27","date_gmt":"2026-07-13T11:43:27","guid":{"rendered":"https:\/\/nostylelike.net\/product\/prograf-tacrolimus-0-5-mg-capsules\/"},"modified":"2026-08-27T14:18:40","modified_gmt":"2026-08-27T11:18:40","slug":"prograf-tacrolimus-0-5-mg-capsules","status":"publish","type":"product","link":"https:\/\/nostylelike.net\/en\/product\/prograf-tacrolimus-0-5-mg-capsules\/","title":{"rendered":"Prograf Tacrolimus 0.5 mg 50 Capsules | Organ Transplant"},"content":{"rendered":"<div class=\"nsl-quick-answer\" style=\"background:#f0f7ff;border-right:4px solid #1e6fd9;border-left:4px solid #1e6fd9;padding:16px;border-radius:8px\">\n<h2>Quick Answer: What Is Prograf Tacrolimus?<\/h2>\n<p><strong>Prograf tacrolimus<\/strong> 0.5 mg is a potent immunosuppressant (calcineurin inhibitor) made by Astellas. It prevents the immune system from attacking and rejecting transplanted organs \u2014 kidney, liver, and heart. Prograf is a lifelong, precisely dosed medicine with a narrow therapeutic window: blood-level (trough) monitoring is mandatory, doses are individualized, and patients must never switch tacrolimus brands or formulations without their transplant team&#8217;s approval.<\/p>\n<\/div>\n<h2>Key Facts About Prograf Tacrolimus 0.5 mg<\/h2>\n<table>\n<tr>\n<th>Product Name<\/th>\n<td>Prograf 0.5 mg Capsules<\/td>\n<\/tr>\n<tr>\n<th>Active Ingredient<\/th>\n<td>Tacrolimus 0.5 mg<\/td>\n<\/tr>\n<tr>\n<th>Drug Class<\/th>\n<td>Calcineurin inhibitor (immunosuppressant)<\/td>\n<\/tr>\n<tr>\n<th>Manufacturer<\/th>\n<td>Astellas Pharma<\/td>\n<\/tr>\n<tr>\n<th>Main Use<\/th>\n<td>Prevention of organ rejection after kidney, liver, or heart transplant<\/td>\n<\/tr>\n<tr>\n<th>Monitoring<\/th>\n<td>Regular tacrolimus trough blood levels + kidney function<\/td>\n<\/tr>\n<tr>\n<th>Prescription Status<\/th>\n<td>Prescription only (specialist supervised)<\/td>\n<\/tr>\n<tr>\n<th>Price in Egypt<\/th>\n<td>1,920 EGP<\/td>\n<\/tr>\n<\/table>\n<p style=\"text-align:center\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/nostylelike.net\/wp-content\/uploads\/2019\/12\/Prograf-5-mg-\u0643\u0628\u0633\u0648\u0644\u0627\u062a-\u2013-\u062f\u0648\u0627\u0621-\u0628\u0631\u0648\u062c\u0631\u0627\u0641-\u0644\u062d\u0645\u0627\u064a\u0629-\u0627\u0644\u0623\u0639\u0636\u0627\u0621-\u0628\u0639\u062f-\u0627\u0644\u0632\u0631\u0627\u0639\u0629-1-1.webp\" alt=\"prograf tacrolimus 0.5 mg immunosuppressant capsules in Egypt\" width=\"600\" height=\"600\" loading=\"lazy\" \/><\/p>\n<h2>How Prograf Tacrolimus Works<\/h2>\n<p>After a transplant, T-lymphocytes recognize the new organ as foreign and mount an attack. Tacrolimus binds to FKBP-12 inside these cells and blocks calcineurin, the enzyme switch that activates them. With calcineurin silenced, T-cells cannot launch the rejection cascade \u2014 the transplanted organ is left in peace while the rest of immunity continues at a reduced, carefully calibrated level.<\/p>\n<h2>How Prograf Is Taken<\/h2>\n<ul>\n<li>Usually twice daily, every 12 hours, at the same times each day.<\/li>\n<li>Take it consistently \u2014 either always with or always without food; food (especially fatty meals) changes absorption.<\/li>\n<li>The 0.5 mg strength allows fine dose adjustments around your target blood level.<\/li>\n<li><strong>Never miss doses and never double up.<\/strong> A missed dose protocol should be agreed with your transplant team in advance.<\/li>\n<li>Swallow capsules whole with water; avoid grapefruit entirely.<\/li>\n<\/ul>\n<h2>The Golden Rules for Transplant Patients<\/h2>\n<ul>\n<li><strong>Never switch brands or generics of tacrolimus<\/strong> (or between immediate- and extended-release) without your transplant center&#8217;s explicit instruction \u2014 small absorption differences can mean rejection or toxicity.<\/li>\n<li>Attend every blood-level appointment; your dose is steered by trough levels, not by how you feel.<\/li>\n<li>Report fever, reduced urine output, pain over the graft, or swelling immediately.<\/li>\n<li>Tell every doctor, dentist, and pharmacist you take tacrolimus before they prescribe anything.<\/li>\n<\/ul>\n<h2>Contraindications<\/h2>\n<ul>\n<li>Known hypersensitivity to tacrolimus or other macrolides.<\/li>\n<li>Combination with cyclosporine is avoided (additive kidney toxicity).<\/li>\n<li>Live vaccines are contraindicated during therapy \u2014 inactivated vaccines are timed with your team.<\/li>\n<\/ul>\n<h2>Possible Side Effects<\/h2>\n<p>Because tacrolimus is powerful, monitoring exists precisely to keep levels in the safe zone. Possible effects include tremor, headache, high blood pressure, elevated blood sugar (post-transplant diabetes), kidney function changes, high potassium, low magnesium, and increased infection susceptibility. Long-term immunosuppression also raises skin cancer risk \u2014 daily sunscreen is standard advice. Most effects are dose-related and manageable with level adjustments.<\/p>\n<h2>Drug and Food Interactions<\/h2>\n<ul>\n<li><strong>Grapefruit and pomelo:<\/strong> strictly forbidden \u2014 they spike tacrolimus levels dangerously.<\/li>\n<li><strong>CYP3A4 inhibitors<\/strong> (ketoconazole, clarithromycin, diltiazem, some antivirals): raise levels \u2014 dose reduction and monitoring needed.<\/li>\n<li><strong>CYP3A4 inducers<\/strong> (rifampicin, St. John&#8217;s Wort, carbamazepine): crash levels and risk rejection.<\/li>\n<li><strong>NSAIDs (ibuprofen, diclofenac):<\/strong> add kidney stress \u2014 use only with medical approval.<\/li>\n<li>Herbal supplements of any kind: check with the transplant pharmacist first, always.<\/li>\n<\/ul>\n<h2>Storage<\/h2>\n<p>Store below 25\u00b0C in the original blister, protected from moisture. Keep out of reach of children.<\/p>\n<h2>Prograf 0.5 mg Price in Egypt<\/h2>\n<p>The price of Prograf tacrolimus 0.5 mg in Egypt is <strong>1,920 EGP<\/strong>. As a critical imported transplant medicine, we prioritize continuous availability \u2014 check the stock status on this page and plan refills at least two weeks ahead so you never run out.<\/p>\n<h2>Related Products<\/h2>\n<p>See our <a href=\"https:\/\/nostylelike.net\/en\/product-category\/immunosuppressant-medications\/\">immunosuppressant medications collection<\/a> at No Style Like.<\/p>\n<h2>Expert Note<\/h2>\n<p>&#8220;With tacrolimus, discipline is the therapy: same times, same brand, no grapefruit, and never skipping a level check. Patients who treat those rules as non-negotiable keep their grafts healthy for decades.&#8221; \u2014 <strong>Dr. Abdallah Fouad, Clinical Nutrition Specialist<\/strong>, 25+ years of pharmaceutical experience.<\/p>\n<h2>Frequently Asked Questions About Prograf Tacrolimus<\/h2>\n<h3>Why must tacrolimus blood levels be checked?<\/h3>\n<p>The gap between too little (rejection) and too much (kidney toxicity) is narrow, and absorption varies between individuals. Trough levels are how your team keeps you in the safe zone.<\/p>\n<h3>Can I switch to a generic tacrolimus?<\/h3>\n<p>Only if your transplant team approves and re-checks your levels after the switch. Never change formulations on your own.<\/p>\n<h3>What if I vomit after a dose?<\/h3>\n<p>Contact your transplant team for their protocol \u2014 do not automatically re-dose.<\/p>\n<h3>Can I fast in Ramadan on Prograf?<\/h3>\n<p>Many stable patients can with an adjusted 12-hour schedule (iftar\/suhoor), but only with your transplant team&#8217;s approval and a level check after the change.<\/p>\n<h3>Why is grapefruit forbidden with Prograf?<\/h3>\n<p>Grapefruit blocks the enzyme that clears tacrolimus, causing sudden toxic level spikes \u2014 even one glass matters.<\/p>\n<h2>Traveling With Your Medicine<\/h2>\n<p>Always carry Prograf in your hand luggage in the original labeled pack, with a copy of your prescription. Split your supply between two bags when possible, carry at least one extra week of capsules, and keep doses on home-time or shift gradually with your team&#8217;s guidance when crossing time zones.<\/p>\n<h2>References<\/h2>\n<p>Tacrolimus clinical profile: <a href=\"https:\/\/go.drugbank.com\/drugs\/DB00864\" rel=\"nofollow noopener\" target=\"_blank\">DrugBank &#8211; Tacrolimus<\/a>.<\/p>\n<p><strong>Bottom line:<\/strong> Prograf tacrolimus 0.5 mg is the fine-tuning strength that keeps transplant immunosuppression precise \u2014 order Prograf tacrolimus from No Style Like and follow your transplant team&#8217;s rules to the letter.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prograf tacrolimus 0.5 mg capsules \u2014 immunosuppressant that protects transplanted organs from rejection. Strictly prescription-only with blood-level monitoring. Price in Egypt: 1,920 EGP.<\/p>\n","protected":false},"featured_media":11358485,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[41603,41753],"product_tag":[],"class_list":["post-11402203","product","type-product","status-publish","has-post-thumbnail","product_cat-immunosuppressant-medications","product_cat-medical-care","first","onbackorder","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product\/11402203","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/comments?post=11402203"}],"version-history":[{"count":2,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product\/11402203\/revisions"}],"predecessor-version":[{"id":11402696,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product\/11402203\/revisions\/11402696"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/media\/11358485"}],"wp:attachment":[{"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/media?parent=11402203"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product_brand?post=11402203"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product_cat?post=11402203"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nostylelike.net\/en\/wp-json\/wp\/v2\/product_tag?post=11402203"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}