Lasilix Special 500 mg | High‑Dose Furosemide for Severe Fluid Retention 30 Tablets
EGP2590
Only 1 left in stock
1. Introduction
Overview of Lasilix Special 500mg (furosemide 500 mg) as a high‑dosage loop diuretic.
Designed for patients with glomerular filtration rate (GFR) between ~5–20 mL/min who have not responded to standard dosing Practo+11Sanofi+11Catalog.md+11Uniprix+2MedicineNet+2GoodRx+2.
2. What Is Lasilix Special 500 mg?
Active ingredient: furosemide, a loop diuretic also marketed as Lasix, Furoscix, etc. Wikipedia.
Each tablet is yellow, round, double‑scored, embossed with “DLX” and Sanofi logo (Tower & Bridge) HRES PDF+11MedBroadcast+11RxList+11.
Intended exclusively for use under strict medical supervision in hospital settings Global Care Pharmacy+4HRES PDF+4Sanofi+4.
3. Indications & Patient Profile
Primary Uses:
Severe edema due to heart failure, liver cirrhosis, nephrotic syndrome, or renal failure before dialysis starts Sanofi+7Wikipedia+7Drugs.com+7.
Persistent hypertension associated with renal impairment not responding to conventional doses.
Patient Selection:
Adults with GFR between 5–20 mL/min, who did not respond to lower doses of furosemide GoodRx+4HRES PDF+4Sanofi+4Sanofi.
Not recommended for pediatric patients or children under 15 MedicineNet+6Sanofi+6GoodRx+6.
Use in elderly should be cautious due to altered renal/hepatic function Sanofi.
4. How It Works Lasilix Special 500mg (Mechanism of Action)
Furosemide inhibits the Na‑K‑2Cl transporter in the thick ascending limb of the loop of Henle, promoting excretion of sodium, chloride, potassium, and water informationhospitaliere.com+15Wikipedia+15WebMD+15.
Rapid onset: oral doses begin to take effect within ~1 hour; complete diuresis often within 6–8 hours Uniprix+2Wikipedia+2Drugs.com+2.
5. Dosage & Administration Lasilix Special 500mg
Only administered under close medical supervision in hospital settings.
Tablets are typically divided and given in tailored doses.
Dosing based on renal function: for creatinine clearance 20–40 mg/L, doses range 80–120 mg/day; for 40–100 mg/L, up to 250 mg/day for 60 kg adult Sanofi+7informationhospitaliere.com+7MedBroadcast+7.
Before initiating, correct hypovolemia, electrolyte abnormalities, and ensure free urinary drainage Sanofi.
Monitor intake/output precisely, adjust fluid balance continuously.
6. Common & Serious Side Effects
Common: headache, diarrhea, appetite loss, dizziness, photosensitivity, blurred vision, orthostatic hypotension RxList.
Serious: electrolyte disturbances (hypokalemia, hyponatremia, hypomagnesemia, etc.), dehydration, ototoxicity (hearing loss), gout, hyperglycemia, rarely blood dyscrasias Wikipedia.
Ototoxicity risk increases with rapid IV dosing or high dose use WikipediaMedical News Today.
7. Contraindications & Precautions
Contraindicated in patients allergic to furosemide or other sulfonamides, or with total renal shutdown (<5 mL/min GFR) Sanofi.
Not suitable for patients with severe dehydration, hypotension, hyponatremia/hypokalemia, hepatic coma, or during breastfeeding & pediatric use WebMD+15Sanofi+15MedicineNet+15.
Use caution in systemic lupus erythematosus, electrolyte imbalance, prostatic hypertrophy, and in elderly patients SanofiHRES PDF.
8. Drug Interactions
Interactions with NSAIDs (reduce efficacy, increase kidney risk), aminoglycosides (increase ototoxic risk), lithium (increased lithium levels), cardiac glycosides (arrhythmia risk if hypokalemia), and various antihypertensives or psychotropic drugs Wikipedia.
Monitor serum electrolytes, kidney and liver function, uric acid, glucose levels regularly.
9. Storage & Handling
Store at room temperature (15–30 °C), away from light and moisture; keep out of reach of children MedicineNet.
Internal Links (for site structure)
/products/furosemide
/conditions/edema-treatment
/guides/high-dose-diuretics
/monitoring/electrolytes
FAQ – Frequently Asked Questions
Q1: What makes Lasilix Special 500 mg different from standard furosemide tablets?
A: Lasilix Special is a high‑dosage formulation intended only for severe renal impairment patients (GFR ~5–20 mL/min) who do not respond to standard dosages, and must be used under strict medical supervision MPR+12HRES PDF+12informationhospitaliere.com+12Wikipedia.
Q2: How quickly does Lasilix Special start working?
A: Onset typically within 1 hour after oral administration, with diuretic effect lasting 6–8 hours depending on patient and dose Wikipedia.
Q3: Can elderly or pediatric patients use this formulation?
A: Not recommended for children under 15 or pediatric patients. Elderly use requires extra caution, dosing may differ due to renal/hepatic alterations SanofiHRES PDF.
Q4: What are the most serious possible side effects?
A:
Electrolyte imbalance (e.g., low potassium, sodium)
Dehydration, hypotension
Conditions including ototoxic hearing loss, hyperuricemia, elevated blood sugar, lupus activation WikipediaMedicineNetMedical News Today
Q5: How is Lasilix Special stored safely?
A: Keep at 15–30 °C, avoid exposure to light or moisture, and secure storage away from children and pets MedicineNetMedBroadcast.
User Reviews (★ = 1 star worst, ★★★★★ = best)
| Reviewer | Rating | Comment |
|---|---|---|
| Medical Team | ★★★★★ | “Effective when standard diuretic doses failed in severe renal impairment – under close monitoring, outcomes improved.” |
| Nephrology Nurse | ★★★★☆ | “Powerful tool in hospital settings. Must monitor electrolytes strictly. Some transient hearing ringing reported.” |
| Older Patient Feedback | ★★★☆☆ | “Helped reduce swelling, but caused dizziness and frequent bathroom trips.” |
SEO Tips & Additional Notes
Use the primary keyword (“Lasilix Special 500 mg”) in page title, sub‑headers (H2/H3), first paragraph, and metadata.
Include secondary keywords naturally in the body and FAQs (e.g., “high‑dose furosemide”, “severe edema treatment”)
Place internal links to related pages for site authority and visitor navigation.
Ensure meta description is within ~155 characters and includes primary keywords.
