Description
Vicks DayQuil and NyQuil SEVERE Cold and Flu 3 Pack (2 Night + 1 Day), 354 mL Each: A Complete 22-Section Guide

Quick answer:
The Vicks DayQuil and NyQuil SEVERE 3 Pack contains three 12 fl oz (354 mL) bottles. You get one non-drowsy DayQuil SEVERE for daytime and two NyQuil SEVERE Berry for nighttime. Together they relieve headache, fever, sore throat, body aches, cough, nasal congestion and a runny nose from colds and flu. Adults and children 12 years and over take 30 mL every 4 hours. Never take more than 4 doses in 24 hours from both bottles combined, because each dose of either product contains acetaminophen.
Key Facts About DayQuil and NyQuil SEVERE
| Name | Vicks DayQuil & NyQuil SEVERE Cold & Flu – 3 Pack (2 Night + 1 Day) |
| Brand | Vicks – Procter & Gamble, USA |
| Pack contents | 1 DayQuil SEVERE + 2 NyQuil SEVERE Berry, 12 fl oz (354 mL) each – 36 fl oz (1.06 L) total |
| DayQuil SEVERE (per 30 mL) | Acetaminophen 650 mg, dextromethorphan HBr 20 mg, guaifenesin 400 mg, phenylephrine HCl 10 mg |
| NyQuil SEVERE (per 30 mL) | Acetaminophen 650 mg, dextromethorphan HBr 20 mg, doxylamine succinate 12.5 mg, phenylephrine HCl 10 mg |
| Dose | 30 mL every 4 hours for adults and children 12+, maximum 4 doses in 24 hours |
| Highlights | Max strength; DayQuil is alcohol-free and non-drowsy; NyQuil for restful nighttime relief |
| Expiry | Printed on the pack |
Short description: DayQuil and NyQuil SEVERE is a complete day-and-night system for severe colds. The daytime liquid relieves symptoms and loosens mucus without drowsiness. The nighttime liquid calms cough, sneezing and a runny nose so you can sleep.
On this page
- Introduction
- What is it?
- How each ingredient works
- Key benefits
- Real-life use cases
- Who is it for?
- Who should avoid it?
- How to use
- Best time to take it
- When will you feel better?
- Common mistakes
- Myths and facts
- Side effects
- Drug interactions
- Warnings
- Signs to monitor
- What to pair it with
- Product comparison
- When to see a doctor
- NSL expert tip
- FAQ
- Conclusion
Introduction to DayQuil and NyQuil SEVERE
A bad cold or flu hits you around the clock. Headache and fever slow you down during the day, then cough and congestion keep you awake at night. That is why Vicks built its famous day-and-night approach: one liquid that keeps you going and another that helps you rest.
This value pack combines one daytime bottle and two nighttime bottles from the SEVERE line, the strongest formula in the Vicks family. In this guide we explain the ingredients of DayQuil and NyQuil, the correct dose, and who needs to be careful.
What Is DayQuil and NyQuil SEVERE?
It is a bundle of two cold and flu symptom relievers made by Vicks, a Procter & Gamble brand. The orange bottle is DayQuil SEVERE for daytime use. It is alcohol-free, non-drowsy and contains an expectorant to loosen chest mucus.
The two blue bottles are NyQuil SEVERE in berry flavor for nighttime use. They contain an antihistamine that eases sneezing and a runny nose and helps you sleep. Each bottle holds 12 fl oz (354 mL) and comes with a marked dosing cup.
How Each Ingredient Works
- Acetaminophen 650 mg: relieves headache, body aches and sore throat, and reduces fever.
- Dextromethorphan HBr 20 mg: a cough suppressant that calms a dry, irritating cough by acting on the cough center in the brain.
- Guaifenesin 400 mg (DayQuil only): an expectorant that thins chest mucus so coughs are more productive.
- Phenylephrine HCl 10 mg: a nasal decongestant aimed at a blocked nose and sinus pressure.
- Doxylamine succinate 12.5 mg (NyQuil only): an antihistamine that reduces sneezing, runny nose and watery eyes, and causes drowsiness that supports sleep.
Key Benefits of DayQuil and NyQuil SEVERE
- Covers the most common cold and flu symptoms: fever, headache, body aches, sore throat, cough and congestion.
- A non-drowsy daytime formula lets you keep working or studying.
- A nighttime formula helps you sleep without constant coughing or a runny nose.
- DayQuil SEVERE loosens mucus that builds up in the chest.
- A three-bottle value pack that covers the whole family or the whole winter season.
- Authentic American product from a brand pharmacists recommend.
Real-Life Use Cases
An employee with the flu: takes DayQuil in the morning and at noon to stay productive, then NyQuil at bedtime to sleep without coughing.
A student during exams: needs relief from headache and congestion during the day without drowsiness, so the daytime bottle fits best.
A family in winter: colds pass between adults at home, so the three-bottle pack costs less than buying single bottles.
Who Is DayQuil and NyQuil For?
- Adults and children aged 12 years and over.
- People with several cold or flu symptoms at the same time.
- Anyone who wants a non-drowsy daytime option and a sleep-friendly nighttime option.
- People with a chesty cough and thick mucus, where DayQuil helps most.
Who Should Avoid It or Ask a Doctor First?
- Children under 12 unless a doctor advises it; never use under 4 years of age.
- People with liver disease or anyone who has 3 or more alcoholic drinks every day.
- People with high blood pressure, heart disease, thyroid disease or diabetes.
- Men with trouble urinating due to an enlarged prostate, and people with glaucoma.
- People with asthma, emphysema, chronic bronchitis or a chronic smoker’s cough.
- Pregnant or breastfeeding women.
- Anyone taking an MAOI antidepressant or who stopped one less than 2 weeks ago.
How to Use DayQuil and NyQuil SEVERE
- Use only the dosing cup provided, never a kitchen spoon.
- Dose: 30 mL every 4 hours for adults and children 12 years and over.
- Use DayQuil during the day and NyQuil in the evening before bed.
- Do not exceed 4 doses in 24 hours from both bottles combined, since every dose contains 650 mg of acetaminophen.
- Do not take any other medicine containing acetaminophen (paracetamol), such as Tylenol or Panadol, at the same time.
Best Time to Take It
A safe sample schedule: DayQuil at 8 a.m. and 12 p.m., then NyQuil at 10 p.m. Take one more NyQuil dose only if needed, at least 4 hours later, without going over 4 doses in total. Avoid NyQuil before driving or any task that needs full alertness.
When Will You Feel Better?
Relief from DayQuil and NyQuil usually starts within about 30 minutes and lasts around 4 hours. However, the liquids treat symptoms and do not shorten the cold itself, which usually improves within 7 to 10 days. See a doctor if cough lasts more than 7 days or fever lasts more than 3 days.
Common Mistakes
- Taking 4 doses of DayQuil and then 4 doses of NyQuil on the same day, which doubles the acetaminophen.
- Combining DayQuil and NyQuil with Panadol tablets or another acetaminophen product.
- Driving after a dose of NyQuil.
- Giving a half dose to a young child without medical advice.
- Using it for weeks to treat a chronic cough without a diagnosis.
Myths and Facts
Myth: a bigger dose means a faster recovery. Fact: extra doses do not speed healing and can damage the liver.
Myth: DayQuil and NyQuil kill the flu virus. Fact: it treats symptoms only; your immune system clears the virus.
Good to know: in 2023 an FDA advisory panel reviewed oral phenylephrine and concluded that its effect on nasal congestion is limited. The other ingredients remain effective for their own symptoms.
Side Effects
- Drowsiness and dizziness, especially with NyQuil.
- Dry mouth.
- Nausea or mild stomach upset.
- Nervousness, sleeplessness or a racing heart from phenylephrine in some people.
- Rarely, a serious skin reaction to acetaminophen; stop immediately if a rash, blisters or peeling appear.
Drug Interactions
- Any other acetaminophen product: risk of overdose.
- MAOI antidepressants: do not combine.
- Sedatives, sleeping pills, other antihistamines and alcohol: increase drowsiness with NyQuil.
- Blood thinners such as warfarin: regular acetaminophen use may affect clotting tests.
- Blood pressure medicines: phenylephrine may reduce their effect.
Warnings
- Liver warning: too much acetaminophen can cause severe liver damage.
- If a severe sore throat lasts more than 2 days or comes with fever, headache, rash, nausea or vomiting, stop and see a doctor.
- Do not drive or operate machinery after taking NyQuil.
- Keep out of reach of children. In case of overdose, get medical help right away, even if you feel fine.
Signs to Monitor
Check your temperature twice a day and watch for shortness of breath, chest pain or wheezing. People with high blood pressure or diabetes should keep monitoring their readings while using DayQuil and NyQuil, because the decongestant may raise blood pressure slightly.
What to Pair It With
- Plenty of warm fluids alongside DayQuil and NyQuil, which help guaifenesin thin mucus.
- Enough sleep and rest.
- Saline nasal rinse or steam for congestion.
- Warm salt-water gargles for a sore throat.
Product Comparison
| Product | What stands out |
|---|---|
| DayQuil and NyQuil SEVERE 3 Pack | Day and night liquids, expectorant, 1.06 L in total |
| Cold & cough products | Browse more cold and flu remedies at No Style Like |
| Panadol Cold & Flu 24 caplets | Tablets for cold symptoms, easy to carry |
When to See a Doctor
- Fever above 39 °C (102 °F) or fever lasting more than 3 days.
- Cough lasting more than 7 days, or coming back with fever, rash or a persistent headache.
- Shortness of breath or chest pain.
- New symptoms, redness or swelling.
- Before using DayQuil and NyQuil if you have a chronic illness or take regular medicines.
NSL Expert Tip
From the No Style Like pharmacy team: the secret to using DayQuil and NyQuil safely is counting. Write down the time of every dose on paper or your phone, and never take more than 4 doses a day from both bottles together. Use the daytime liquid for work, save the nighttime liquid for sleep, and do not add any other acetaminophen painkiller.
DayQuil and NyQuil FAQ
What is the difference between DayQuil and NyQuil?
DayQuil is a non-drowsy daytime formula with an expectorant. NyQuil is a nighttime formula with an antihistamine that eases a runny nose and helps you sleep.
Can I take both on the same day?
Yes, as long as the total from both does not exceed 4 doses in 24 hours, with at least 4 hours between doses.
Is it suitable for children?
The label dose is for adults and children 12 and over. Children aged 4 to 12 should only use it on a doctor’s advice, and it must not be used under age 4.
Does it cause drowsiness?
NyQuil causes drowsiness; DayQuil usually does not.
Can I take it while pregnant?
Do not use it during pregnancy or breastfeeding unless your doctor approves.
What is the expiry date?
The expiry date is printed on the pack.
Conclusion
Vicks DayQuil and NyQuil SEVERE is a three-bottle value pack that treats severe cold and flu symptoms day and night. The daytime liquid is non-drowsy and loosens mucus, while the nighttime liquid helps you sleep. Stick to the dose and the daily limit, and never combine it with other acetaminophen products. Order DayQuil and NyQuil today from No Style Like Pharmacy with delivery across Egypt.
Reviewed by the No Style Like Pharmacy content team. This information is for educational purposes only.
Read the leaflet and follow the label or your doctor’s directions; this content does not replace medical advice. Learn more at MedlinePlus – Acetaminophen.










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